Calcium Phosphate Ion Clusters (CPICs) - An Exclusive Pac-Dent Biomimetic Enamel Regeneration Technology
Calcium Phosphate Ionic Clusters (CPICs) are a Pac-Dent’s exclusive biomimetic technology designed to support natural enamel reminerlization. These nano-sized, bioactive mineral clusters penetrate demineralized enamel and exposed dentin, helping the tooth form new hydroxyapatite as part of its natural mineral structure. This supports enamel from within rather than simply coating the surface.
By mimicking the body’s natural mineralization process, CPICs also supports dentinal tubules, assisting in long-lasting sensitivity relief. This provides a more biologically relevant approach to enamel support than traditional remineralization technologies.
Desensitizing Paste with Enamel-Support Technology
ProMin™ F
ProMin™ F is a fluoride-containing CPIC paste designed for daily enamel support. It delivers calcium, phosphate, and fluoride to help maintain mineral balance when saliva alone may be insufficient, reducing the risk of demineralization and sensitivity.
ProMin™ F is suitable for a wide range of patients, including children and adults, and is especially beneficial for individuals with dry mouth, orthodontic appliances, enamel wear, or tooth sensitivity. It is free of milk proteins, gluten, peanuts, sodium lauryl sulfate, and triclosan, making it appropriate for patients with dietary restrictions or ingredient sensitivities. ProMin™ F is also available in a travel-friendly pen format for targeted application.
ProMin™
ProMin™ is a fluoride-free CPIC paste. It is ideal for patients who prefer non-fluoride care while still benefiting from CPIC-driven remineralization support.
Why Recommend ProMin™ F & ProMin™ ？
● Supports Beyond the Surface: Bioactive CPIC support enamel, dentin subsurfaces and tubules reminerlization—not just surface coating.
● Deep Nano-Cluster Penetration: Ultra-small CPIC clusters penetrate demineralized enamel to help remineralize the enamel substructure.
● Long-Lasting Sensitivity Relief: Helps remineralize and reinforce dentinal tubules to help reduce sensitivity over time.
● Suitable for patients with reduced salivary flow: ProMin™ F supplies calcium, phosphate, and fluoride to help maintain mineral balance when salivary protection is reduced.
● Clean, Patient-Friendly Formula: Suitable for both children and adults. Free of milk proteins, gluten, peanuts, sodium lauryl sulfate, and triclosan.
